What are the two most common causes of iron deficiency anemia in adults attributed to?

The two most common causes of iron deficiency anemia in adults can be attributed to gynecologic losses and bleeding in the gastrointestinal (GI) tract. Gynecologic losses commonly include menstrual bleeding, particularly in women of reproductive age, where heavy periods can lead to significant iron loss.

In addition, bleeding from the GI tract is a prevalent cause of iron deficiency anemia in both men and women, especially as individuals age or in those with certain health conditions such as ulcers, malignancies, or diverticulosis. This type of bleeding may often be occult and go unnoticed until it leads to anemia.

Addressing both of these factors is crucial in diagnosing and managing iron deficiency anemia in adults. Other options focus on causes that are less commonly recognized as primary contributors to iron deficiency anemia in this population. For instance, while chronic disease can contribute to anemia, it typically leads to anemia of chronic disease rather than iron deficiency specifically.