What should be ordered next for Mr. Brown, a 45-year-old African American male, who has lab values showing a cholesterol level of 250?

In the context of managing hyperlipidemia, particularly in a patient like Mr. Brown who has a cholesterol level of 250, the next appropriate step involves assessing and ruling out other potential underlying causes for elevated cholesterol levels. Ordering a thyroid-stimulating hormone (TSH) test is relevant because hypothyroidism can lead to increased cholesterol levels. If the thyroid function is impaired, addressing this issue can help normalize cholesterol levels and provide a more comprehensive view of the patient's health status.

While a lipid panel would provide additional details about the specific components of Mr. Brown's cholesterol levels, it’s important to first consider other systemic issues that could affect cholesterol metabolism. A complete blood count (CBC) and a blood glucose test may not offer relevant insights specific to the immediate management of elevated cholesterol levels in comparison to assessing thyroid function, especially given the presenting concern. Therefore, by ordering the TSH test next, it allows for a broader understanding of the physiological factors contributing to Mr. Brown's hyperlipidemia.